Targeted Relief for Gastrointestinal Harmony
Clinically effective and safe option in the empirical management of acute diarrhea of various etiologies. [Arif Ahmad Faruqui AA., 2023]
RIFAXIMIN
- Has Broad spectrum activity.
- Inhibits bacterial RNA synthesis and restores intestinal microflora imbalance.
- A pregnane X receptor (PXR) activator that inhibits inflammatory bowel disease (IBD). [Drug bank DB01220].
- Diminish deaminating enteric bacteria.
- Efficacious regimen for co-infectious diarrhea treatment. [Flamm SL. Rifaximin, 2011]
- Effective against CDI [Berman AL et. al., 2007]
METRONIDAZOLE
- Inhibits synthesis of bacterial and protozoal DNA by binding and inhibiting its replication. [Drug bank DB00916]
- Shows clinical efficacy and safety in case of diarrhea and CDAD [Faruqui AA., 2023]
- Targets pathogens involved in causing co-infectious diarrhea
- Combination ensures a decrease in gastro-intestinal infections where co-infection is the norm’
Indications:
- Traveler’s diarrhea
- Hepatic encephalopathy recurrence
- Irritable bowel syndrome with diarrhea (IBS-D)
